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PAD POST VASCULAR INTERVENTION : Learning About XARELTO® | Xarelto® (rivaroxaban) Welcome Kit

Learning About XARELTO®


Having a procedure. Starting therapy. All of this can be daunting and overwhelming. But you can be reassured that, together with a few tips, support, and commitment, it's possible to start on the right track. First things first, be sure to fill your XARELTO® (rivaroxaban) prescription if you haven’t yet.

What is XARELTO®?

XARELTO® belongs to a group of medicines called direct oral anticoagulants, or DOACs for short. Like other DOACs, XARELTO® has no known dietary restrictions, no requirements for frequent blood tests, and few drug interactions.

How does XARELTO® work with aspirin?

Both XARELTO® and aspirin help prevent serious blood clots from forming and growing—but they work in different ways:

  • XARELTO® slows your body's ability to clot by selectively blocking one of the clotting factors found in your blood—an enzyme called Factor Xa ("10a").
  • Aspirin is an antiplatelet blood thinner that works by helping to keep platelets (which are pieces of blood cells) from sticking together and forming blood clots.

XARELTO® for People With PAD

XARELTO®, in combination with low-dose aspirin, may help reduce the risk of a sudden decrease in blood flow to the legs, major amputation, serious heart problems, and stroke in adults with PAD.

almost85%Did not have
a major blood-clotting
event after vascular intervention*

Significantly reduces hospitalizations and additional procedures after vascular intervention.

In a clinical study, almost 85% of people who took XARELTO®, in combination with low-dose aspirin, did not have a heart attack, stroke, sudden decrease in blood flow in the legs, or amputation after vascular intervention. XARELTO® is also proven to significantly reduce the need for additional vascular procedures or hospitalization due to blood-flow issues in the legs.

*The rate of a first event like a stroke, heart attack, poor blood flow in the legs, and amputation was 15.5% for people taking XARELTO® plus aspirin versus 17.8% for aspirin alone. Patients were followed for an average length of treatment of 30 months.

Remember, all blood thinners come with a risk of bleeding. Less than 2% of people taking XARELTO®, in combination with aspirin, experienced major bleeding versus 1% of people taking only low-dose aspirin.